Focused Ultrasound Strategies for Brain Tumor Therapy
نویسندگان
چکیده
منابع مشابه
Strategies for reducing regulatory barriers to focused ultrasound technology
Background/introduction The U.S. Food and Drug Administration (FDA) has automatically classified focused ultrasound (FUS) devices Class III, which requires sponsors to demonstrate the safety and effectiveness of a device through clinical trials. This requirement adds significant time and cost to the device development process; reclassification to Class II would be highly beneficial for the futu...
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We demonstrated the in vivo feasibility of using focused ultrasound (FUS) to transiently modulate (through either stimulation or suppression) the function of regional brain tissue in rabbits. FUS was delivered in a train of pulses at low acoustic energy, far below the cavitation threshold, to the animal's somatomotor and visual areas, as guided by anatomical and functional information from magn...
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This paper provides a historic and contemporary overview of the use of focused ultrasound for treating brain disorders.
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Introduction Brain therapy with transcranial focused ultrasound is a scientific and technological challenge [1,2]. A novel prototype is presented here (SuperSonic Imagine, France), working at the highest frequency envisioned currently for transcranial brain treatment (1MHz). A non invasive time-reversal focusing technique based on CT scans is performed for that purpose [3]. Such a brain therapy...
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BACKGROUND Glioblastoma is a notoriously difficult tumor to treat because of its relative sanctuary in the brain and infiltrative behavior. Therapies need to penetrate the CNS but avoid collateral tissue injury. Boron neutron capture therapy (BNCT) is a treatment whereby a (10)B-containing drug preferentially accumulates in malignant cells and causes highly localized damage when exposed to epit...
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ژورنال
عنوان ژورنال: Operative Neurosurgery
سال: 2019
ISSN: 2332-4252,2332-4260
DOI: 10.1093/ons/opz374